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Laboratory","2025-06-04T04:46:43.467Z","2025-06-08T22:32:06.022Z","2025-06-04T05:02:31.059Z","153",{"id":1555,"name":1556,"alternativeText":16,"caption":16,"width":1557,"height":1558,"formats":1559,"hash":1582,"ext":953,"mime":915,"size":1583,"url":1584,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1585,"updatedAt":1585},168,"NPLPrimaryLogoBlueRGB.jpg",2953,1089,{"large":1560,"small":1565,"medium":1571,"thumbnail":1576},{"ext":953,"url":1561,"hash":1562,"mime":915,"name":1563,"path":16,"size":769,"width":958,"height":1564},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_NPL_Primary_Logo_Blue_RGB_2501e310eb.jpg","large_NPL_Primary_Logo_Blue_RGB_2501e310eb","large_NPLPrimaryLogoBlueRGB.jpg",369,{"ext":953,"url":1566,"hash":1567,"mime":915,"name":1568,"path":16,"size":1569,"width":873,"height":1570},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_NPL_Primary_Logo_Blue_RGB_2501e310eb.jpg","small_NPL_Primary_Logo_Blue_RGB_2501e310eb","small_NPLPrimaryLogoBlueRGB.jpg",18.41,184,{"ext":953,"url":1572,"hash":1573,"mime":915,"name":1574,"path":16,"size":1575,"width":880,"height":1244},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/medium_NPL_Primary_Logo_Blue_RGB_2501e310eb.jpg","medium_NPL_Primary_Logo_Blue_RGB_2501e310eb","medium_NPLPrimaryLogoBlueRGB.jpg",31.88,{"ext":953,"url":1577,"hash":1578,"mime":915,"name":1579,"path":16,"size":1580,"width":1022,"height":1581},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_NPL_Primary_Logo_Blue_RGB_2501e310eb.jpg","thumbnail_NPL_Primary_Logo_Blue_RGB_2501e310eb","thumbnail_NPLPrimaryLogoBlueRGB.jpg",6.93,90,"NPL_Primary_Logo_Blue_RGB_2501e310eb",181.98,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/NPL_Primary_Logo_Blue_RGB_2501e310eb.jpg","2025-06-04T02:44:55.203Z",{"id":343,"variation":39,"button":1587},[1588],{"id":167,"label":896,"size":832,"color":833,"style":16,"icon":834,"iconPosition":835,"url":1589,"newWindow":8,"downloadable":16,"shape":16},"https://www.npl.co.uk/","-127",{"id":241,"name":1592,"description":50,"createdAt":1593,"updatedAt":1594,"publishedAt":1595,"url_path_id":1596,"logo":1597,"website":1616,"url_path":1620},"us4us Ltd.","2025-06-04T04:59:19.195Z","2025-06-08T22:31:10.604Z","2025-06-04T05:02:23.543Z","154",{"id":1598,"name":1599,"alternativeText":16,"caption":16,"width":1600,"height":1601,"formats":1602,"hash":1612,"ext":19,"mime":20,"size":1613,"url":1614,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1615,"updatedAt":1615},169,"us4us(R)-logo.png",555,177,{"small":1603,"thumbnail":1607},{"ext":19,"url":1604,"hash":1605,"mime":20,"name":1606,"path":16,"size":358,"width":873,"height":1100},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_us4us_R_logo_6e902c6444.png","small_us4us_R_logo_6e902c6444","small_us4us(R)-logo.png",{"ext":19,"url":1608,"hash":1609,"mime":20,"name":1610,"path":16,"size":1611,"width":1022,"height":1112},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_us4us_R_logo_6e902c6444.png","thumbnail_us4us_R_logo_6e902c6444","thumbnail_us4us(R)-logo.png",5.06,"us4us_R_logo_6e902c6444",2.38,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/us4us_R_logo_6e902c6444.png","2025-06-04T04:58:43.571Z",{"id":325,"variation":39,"button":1617},[1618],{"id":161,"label":896,"size":832,"color":833,"style":16,"icon":834,"iconPosition":835,"url":1619,"newWindow":8,"downloadable":16,"shape":16},"https://us4us.eu","-128",{"id":187,"name":1622,"description":50,"createdAt":1623,"updatedAt":1624,"publishedAt":1625,"url_path_id":1626,"logo":1627,"website":1658,"url_path":1662},"Sound & Bright","2025-06-05T04:17:16.587Z","2025-06-08T22:33:30.491Z","2025-06-05T04:17:24.995Z","155",{"id":412,"name":1628,"alternativeText":16,"caption":16,"width":1629,"height":1630,"formats":1631,"hash":1654,"ext":19,"mime":20,"size":1655,"url":1656,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1657,"updatedAt":1657},"logo (5).png",1596,870,{"large":1632,"small":1637,"medium":1642,"thumbnail":1648},{"ext":19,"url":1633,"hash":1634,"mime":20,"name":1635,"path":16,"size":1636,"width":958,"height":924},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_logo_5_16a1aaa948.png","large_logo_5_16a1aaa948","large_logo (5).png",82.62,{"ext":19,"url":1638,"hash":1639,"mime":20,"name":1640,"path":16,"size":1641,"width":873,"height":1330},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_logo_5_16a1aaa948.png","small_logo_5_16a1aaa948","small_logo (5).png",36.29,{"ext":19,"url":1643,"hash":1644,"mime":20,"name":1645,"path":16,"size":1646,"width":880,"height":1647},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/medium_logo_5_16a1aaa948.png","medium_logo_5_16a1aaa948","medium_logo (5).png",58.31,409,{"ext":19,"url":1649,"hash":1650,"mime":20,"name":1651,"path":16,"size":1652,"width":1022,"height":1653},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_logo_5_16a1aaa948.png","thumbnail_logo_5_16a1aaa948","thumbnail_logo (5).png",16.54,134,"logo_5_16a1aaa948",23.01,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/logo_5_16a1aaa948.png","2025-06-05T19:07:19.097Z",{"id":300,"variation":39,"button":1659},[1660],{"id":363,"label":896,"size":832,"color":833,"style":16,"icon":834,"iconPosition":835,"url":1661,"newWindow":8,"downloadable":16,"shape":16},"https://soundnbright.com/","-129",{"id":181,"name":1664,"description":50,"createdAt":1665,"updatedAt":1666,"publishedAt":1667,"url_path_id":1668,"logo":1669,"website":1683,"url_path":1687},"S-Sharp Corporation","2025-06-05T04:37:04.462Z","2025-06-17T05:02:24.932Z","2025-06-05T04:37:08.560Z","156",{"id":607,"name":1670,"alternativeText":16,"caption":16,"width":1671,"height":1672,"formats":1673,"hash":1679,"ext":19,"mime":20,"size":1680,"url":1681,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1682,"updatedAt":1682},"S-Sharp.png",428,107,{"thumbnail":1674},{"ext":19,"url":1675,"hash":1676,"mime":20,"name":1677,"path":16,"size":1678,"width":1022,"height":906},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_S_Sharp_df3154935a.png","thumbnail_S_Sharp_df3154935a","thumbnail_S-Sharp.png",6.75,"S_Sharp_df3154935a",2.35,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/S_Sharp_df3154935a.png","2025-06-05T04:36:37.902Z",{"id":117,"variation":39,"button":1684},[1685],{"id":793,"label":896,"size":832,"color":833,"style":16,"icon":834,"iconPosition":835,"url":1686,"newWindow":8,"downloadable":16,"shape":16},"https://www.s-sharp.com/web/index/index.jsp","-130",{"pagination":1689},{"page":5,"pageSize":181,"pageCount":46,"total":363},{"id":267,"heading":262,"pageHeader":1691,"sections":1692},{"id":207,"description":16,"showPageHeader":8,"backgroundColor":54,"image":16},[1693],{"id":46,"__component":1694,"componentVariation":1695,"contactsVariation":1696,"styles":16,"header":16,"sessionsGroup":1697},"content.sessions","Sessions Base","Card Contact Full",[1698,1957,2058,2098,2202,2318],{"id":77,"groupTitle":1699,"sessions":1700},"Group 1",[1701,1732,1765,1794,1838,1874,1925],{"id":325,"session":1702},{"id":155,"title":1703,"teaser":1704,"body":50,"createdAt":1705,"updatedAt":1705,"publishedAt":16,"url_path_id":1706,"contacts":1707,"url_path":1731},"High-Frequency Ultrafast Ultrasound Imaging for High-Resolution Elastography and Blood Flow Mapping","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Ultrasound imaging is widely used in various clinical applications due to its non-invasive nature and real-time imaging capabilities. To enhance spatial resolution, high-frequency ultrasound imaging (>30 MHz) has been developed and applied in specialized areas such as ophthalmology, dermatology, and small animal research. However, conventional high frequency ultrasound imaging typically employs a line-by-line scanning method, which captures only a few tissue signal samples over a given period. This limitation significantly reduces the frame rate, particularly hindering the tracking of dynamic tissue motion—such as blood flow and shear wave propagation. To overcome this challenge, ultrafast ultrasound imaging has been introduced. This technique enables high-frame-rate imaging and has shown promise in applications such as small vessel blood flow mapping and ultrasonic shear wave elastography. In this presentation, I will present our integrated approach that combines high-frequency ultrasound with ultrafast imaging. I will explore advanced imaging techniques including super-resolution blood flow imaging and high-resolution ultrasound elastography. Specific applications will be discussed, including elastography and blood flow mapping in mouse brain, elastography of the eye and human tendons, and vector Doppler imaging for mapping small peripheral vessels in humans.\u003C/span>\u003C/p>","2025-04-18T13:40:32.042Z","119",[1708],{"id":1206,"name":1709,"committee":16,"position":16,"affiliation":1710,"email":16,"biography":1711,"createdAt":1712,"updatedAt":1712,"url_path_id":1713,"contactPhoto":1714,"socialLinks":1729,"url_path":1730},"Chih-Chung Huang","National Cheng Kung University","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Chih-Chung Huang was born in Taoyuan, Taiwan. He earned his B.S., M.S., and Ph.D. degrees in Biomedical Engineering from Chung Yuan Christian University in Chung-Li, Taiwan, in 2002, 2003, and 2007, respectively. From 2006 to 2007, he worked as a Visiting Researcher at the NIH Resource Center for Medical Ultrasonic Transducer Technology at the University of Southern California, Los Angeles, USA, where he conducted research on high-frequency ultrasound imaging. In 2008, Dr. Huang joined the Department of Electrical Engineering at Fu Jen Catholic University, Taiwan, as an Assistant Professor. In 2013, he moved to the Department of Biomedical Engineering at National Cheng Kung University, Taiwan, where he is currently a Distinguished Professor. Dr. Huang has held several key administrative roles, including Deputy Director of the Medical Device Innovation Center, Deputy Director of the Technology Transfer & Business Incubation Center, and Strategic Planning Division Director of the Research & Services Headquarters at National Cheng Kung University. He also served as the Secretary General of the Taiwanese Society of Biomedical Engineering. His research interests focus on ultrasonic tissue characterization, blood flow measurement, high-frequency ultrasound, and the development of ultrasonic instruments for medical applications. Dr. Huang was selected as a member of the IFMBE Asia-Pacific Research Networking Fellowship and serves as an ordinary member of the CoS representative of the Taiwanese Society of Biomedical Engineering, which is affiliated with the IFMBE. He is an associate editor for \u003Ci>Medical Physics\u003C/i> and the \u003Ci>Journal of Medical and Biological Engineering\u003C/i>. Dr. Huang is a senior member of IEEE and serves as a TPC member of IEEE IUS.\u003C/span>\u003C/p>","2025-04-18T13:39:53.212Z","118",{"id":1715,"name":1716,"alternativeText":16,"caption":16,"width":1555,"height":1717,"formats":1718,"hash":1725,"ext":19,"mime":20,"size":1726,"url":1727,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1728,"updatedAt":1728},124,"Screenshot 2025-04-18 084037.png",189,{"thumbnail":1719},{"ext":19,"url":1720,"hash":1721,"mime":20,"name":1722,"path":16,"size":1723,"width":1724,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Screenshot_2025_04_18_084037_f5c7341775.png","thumbnail_Screenshot_2025_04_18_084037_f5c7341775","thumbnail_Screenshot 2025-04-18 084037.png",45.48,139,"Screenshot_2025_04_18_084037_f5c7341775",17.69,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Screenshot_2025_04_18_084037_f5c7341775.png","2025-04-18T13:39:25.913Z",[],"-98","-99",{"id":124,"session":1733},{"id":267,"title":1734,"teaser":1735,"body":50,"createdAt":1736,"updatedAt":1736,"publishedAt":16,"url_path_id":1737,"contacts":1738,"url_path":1764},"Nonlinear Sound-Sheet Microscopy","\u003Cp style=\"text-align:justify;\">Genetically encoded gas vesicles provide an alternative to light for deep tissue cellular imaging. For this technology to be used to its fullest, the collaboration between chemical engineering and applied physics must continue so that biologists can visualize and track cells on an organ scale. In this talk, I will review the development of a contrast-enhanced imaging paradigm based on the transmission of supersonic X-waves. This approach culminated in the introduction of nonlinear sound-sheet microscopy (NSSM), a three-dimensional high-frequency method that sweeps thin ultrasound sheets through biological tissues labeled with contrast agents.\u003Cbr>\u003Cbr>NSSM relies on the transmission of cross-propagating plane waves that intersect along thin tissue sections referred to as sound sheets. At the intersection of the two waves, acoustic pressure is doubled. The full NSSM sequence consists in subsequently probing the medium with single plane wave transmissions. In doing so, ultrasound contrast agents experience a modulation of acoustic pressure if and only if they are located within the sound sheet plane.\u003Cbr>This amplitude modulation approach based on the geometric interaction of two wavefronts was developed to decouple nonlinear effects arising from wave propagation and nonlinear scattering of ultrasound contrast agents, and achieve highly imaging of microbubbles or gas vesicles. To maximize volumetric field-of-view at high frequency (15 MHz), NSSM was implemented on row-column arrays that provide the necessary degrees of freedom to operate this imaging mode.\u003Cbr>\u003Cbr>Using NSSM, we successfully detected bacterial and mammalian cells expressing GVs in a cubic centimeter volume. By visualizing GV expression in cancer cells, NSSM enabled longitudinal tracking of tumor progression and the quantification of necrotic core volumes. Lipid-shelled microbubbles are also agents observable with amplitude modulation sequences. We showed that NSSM at kilohertz framerate enables selective-plane, nonlinear ultrafast\u003Cbr>Doppler imaging of rodent brains perfused with microbubbles. Lastly, we report ultrasound imaging of cerebral capillaries using nonlinear sound sheet localization microscopy, a super-resolution method sensitive to slowest cerebral blood flows. The combination of synthetic and molecular ultrasound contrast agents with fast, high-resolution and volumetric imaging methods carries a wave of opportunities for the field of (bio)molecular ultrasound.\u003Cbr> \u003C/p>","2025-04-18T13:36:40.544Z","117",[1739],{"id":1740,"name":1741,"committee":16,"position":16,"affiliation":1742,"email":16,"biography":1743,"createdAt":1744,"updatedAt":1745,"url_path_id":1746,"contactPhoto":1747,"socialLinks":1762,"url_path":1763},51,"David Maresca","Delft University of Technology","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Dr Maresca heads the Maresca Laboratory at Delft University of Technology, the Netherlands. The Maresca Lab develops ultrasound methods capable of visualizing dynamic biological processes across space and time. One of the Lab’s key contributions is the introduction of nonlinear sound-sheet microscopy, a method relying on thin sound sheets to visualize organs at the level of capillaries and cells. Dr. Maresca is an associate professor of Imaging Physics at TU Delft.\u003C/span>\u003C/p>","2025-03-31T15:46:22.830Z","2025-04-01T23:21:10.751Z","87",{"id":1748,"name":1749,"alternativeText":16,"caption":16,"width":1750,"height":1751,"formats":1752,"hash":1758,"ext":19,"mime":20,"size":1759,"url":1760,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1761,"updatedAt":1761},91,"David Maresca Headshot - David Maresca.png",257,260,{"thumbnail":1753},{"ext":19,"url":1754,"hash":1755,"mime":20,"name":1756,"path":16,"size":1757,"width":1365,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_David_Maresca_Headshot_David_Maresca_870d114f49.png","thumbnail_David_Maresca_Headshot_David_Maresca_870d114f49","thumbnail_David Maresca Headshot - David Maresca.png",34.94,"David_Maresca_Headshot_David_Maresca_870d114f49",24.74,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/David_Maresca_Headshot_David_Maresca_870d114f49.png","2025-03-31T15:46:06.905Z",[],"-67","-97",{"id":300,"session":1766},{"id":561,"title":1767,"teaser":1768,"body":50,"createdAt":1769,"updatedAt":1769,"publishedAt":16,"url_path_id":1770,"contacts":1771,"url_path":1793},"High-speed imaging of intraventricular flow patterns for murine cardiovascular studies","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Advanced ultrasound flow imaging methods such as speckle tracking and vector flow have been of interest for human intraventricular flow imaging in the left ventricle because of the potential to capture subtle deviations from normal heart function. However, reducing the complicated flow patterns into more basic quantities that describe disease progression or normal/abnormal behavior continues to be a major research topic in the quest to translate flow pattern imaging into clinical practice. As is often the case, murine models make excellent candidates to study cardiovascular disease and ultrasound methods are a common tool to quantify cardiac functional parameters. Translating methods proven effective in humans to mice is challenging because of the smaller scale of the mouse heart and a heart rate that is ~10x faster than humans. We have developed a pipeline for multi-angle, plane-wave vector-flow imaging in the murine left ventricle. We initially validated the approach using a Verasonics Vantage with a 15-MHz linear array in a knockout mouse model with a temperature sensitive arrythmia and demonstrated we could quantify changes in vorticity. We are presently undertaking studies with a mouse model of hypertrophy using a 30-MHz linear array and a Verasonics NXT. The increased transmit frequency results in significant aliasing artifacts which we addressed be implementing a double transmit scheme combined with a staggered pulse repetition frequency. Our approach extends the unambiguous velocity range by ~6x verses conventional multi-angle vector flow and permits robust vector-flow estimates.  After establishing repeatability of the method over a range of mouse ages, we performed a longitudinal study as hypertrophy developed to quantify the changes in quantities such as vorticity and energy loss. While the methods we are developing have the potential to inform quantification of flow in the human heart, our focus is on advancing the state of the art for murine cardiac functional imaging.\u003C/span>\u003C/p>\u003Cp>\u003Cbr> \u003C/p>","2025-04-18T13:28:39.823Z","114",[1772],{"id":1173,"name":1773,"committee":16,"position":16,"affiliation":1774,"email":16,"biography":1775,"createdAt":1776,"updatedAt":1777,"url_path_id":1778,"contactPhoto":1779,"socialLinks":1791,"url_path":1792},"Jeffrey A. Ketterling","Weill Cornell Medicine","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Jeff Ketterling is Professor of Biomedical Engineering in Radiology, Weill Cornell Medicine (WCM) in New York City. After his graduate studies at Yale University and prior to working at WCM, Jeff worked for 23 years as a research scientist at Riverside Research Institute, New York, NY.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Jeff’s research is focused on the development and translation of ultrasound technology to basic science, small-animal and clinical applications. He has worked extensively with high-frequency ultrasound (> 20 MHz). He developed a method of fabricating annular-array transducers and designed imaging platforms for ophthalmic human use and mouse embryonic central nervous system development. The work was extended to in vivo photoacoustic imaging of mouse embryos. More recent projects include high-frequency, high-speed plane-wave ultrasound imaging such as intracardiac flow patterns in adult mouse cardiac disease models, blood flow in the front and back of the human eye, and activation of acoustic nanodrops for imaging microcirculation using methods such as super-resolution localization microscopy.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Jeff served as the Chair of the Medical Ultrasonics Technical Program Committee of the IEEE-IUS from 2019-2021 and was the Technical Chair for the Biomedical Acoustics Committee of the Acoustical Society of America from 2008-2011.\u003C/span>\u003C/p>\u003Cp>\u003Cbr> \u003C/p>","2025-04-18T13:26:42.069Z","2025-08-29T23:36:53.961Z","113",{"id":1022,"name":1780,"alternativeText":16,"caption":16,"width":965,"height":965,"formats":1781,"hash":1787,"ext":953,"mime":915,"size":1788,"url":1789,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1790,"updatedAt":1790},"wcm_jeffrey_ketterling_2674_edit.jpg",{"thumbnail":1782},{"ext":953,"url":1783,"hash":1784,"mime":915,"name":1785,"path":16,"size":1786,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_wcm_jeffrey_ketterling_2674_edit_6b0a768284.jpg","thumbnail_wcm_jeffrey_ketterling_2674_edit_6b0a768284","thumbnail_wcm_jeffrey_ketterling_2674_edit.jpg",4.68,"wcm_jeffrey_ketterling_2674_edit_6b0a768284",14.28,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/wcm_jeffrey_ketterling_2674_edit_6b0a768284.jpg","2025-08-29T23:36:51.403Z",[],"-93","-94",{"id":117,"session":1795},{"id":221,"title":1796,"teaser":1797,"body":50,"createdAt":1798,"updatedAt":1798,"publishedAt":16,"url_path_id":1799,"contacts":1800,"url_path":1837},"Distributed Aberration Correction in Pulse-Echo Ultrasound via Sound-Speed-Adapting Beamformers","\u003Cp style=\"text-align:justify;\">The speed of sound of tissue plays a fundamental role in the formation of ultrasound images. Typically, the speed of sound in tissue is assumed to be a constant 1540 m/s, which is the average speed of sound of soft tissue in the human body. The assumption of a constant speed of sound is advantageous because it simplifies the computation of the image reconstruction process. However, the true speed at which the acoustic waves propagate varies with the local tissue, and differences between the assumed and true speed of sound cause distortion of the acoustic wave, familiarly known as aberration. Aberration leads to degraded and suboptimal image quality, reduced resolution, increased image noise, and loss of diagnostic confidence.\u003Cbr>\u003Cbr>In this talk, we explore a range of sound speed estimation techniques for distributed aberration correction in pulse-echo ultrasound. Estimation of the speed of sound becomes a challenging problem, because the assumption of a heterogeneous speed of sound for a medium leads to unknown positions of the echoes. We begin with simple inversion models relating the propagation average speed of sound to the localized speed of sound and work our way up to more complicated time-of-flight tomography models. These estimates are then used to achieve distributed aberration correction through sound-speed-adapting beamformers, or beamformers that can accommodate heterogeneous sound speed and corrects the entire ultrasound image based on the pixel-by-pixel estimated speed of sound.\u003Cbr>\u003Cbr>We demonstrate distributed aberration correction techniques, including straight-ray beamforming, eikonal beamforming, and wavefield correlation, including these methods incorporated into differentiable beamforming. The results of these techniques are shown in a variety of phantoms and in vivo examples. Using early inversion sound speed models, distributed aberration correction was successful in simple layered geometries, but lacked\u003Cbr>improvement over more complex distributions of sound speed. Building upon these earlier methods, we developed distributed aberration correction with differentiable beamforming, which iterates between sound speed estimation and image focusing and converges into a well-focused image under heterogenous sound speed conditions. We demonstrate the power of this iterative method from in vivo images in the liver, showing dramatic changes in image quality and potentially establishing new directions for distributed aberration correction.\u003C/p>","2025-04-18T13:45:12.673Z","121",[1801],{"id":1348,"name":1802,"committee":16,"position":16,"affiliation":1803,"email":16,"biography":1804,"createdAt":1805,"updatedAt":1805,"url_path_id":1806,"contactPhoto":1807,"socialLinks":1835,"url_path":1836},"Jeremy Dahl","Stanford University","\u003Cp style=\"text-align:justify;\">Jeremy Dahl, PhD, is an Associate Professor of Radiology at Stanford University in the School of Medicine, with appointments in the divisions of Pediatric Radiology, the Radiological Sciences Laboratory, and the Diagnostic Sciences Laboratory (formerly the Canary Center for Cancer Early Detection). His research focus includes ultrasound image reconstruction and beamforming methods to improve image quality and reduce image noise for the difficult-to-image population. This includes methods such as sound speed estimation for distributed aberration correction and methods to reduce diffuse reverberation noise. In addition to improving ultrasound image quality, he is also exploring ultrasound molecular imaging platforms for early cancer detection.\u003C/p>","2025-04-18T13:42:24.267Z","120",{"id":1808,"name":1809,"alternativeText":16,"caption":16,"width":1810,"height":1811,"formats":1812,"hash":1831,"ext":19,"mime":20,"size":1832,"url":1833,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1834,"updatedAt":1834},125,"jeremy_dahl_headshot - Jeremy Dahl.png",845,900,{"small":1813,"medium":1819,"thumbnail":1825},{"ext":19,"url":1814,"hash":1815,"mime":20,"name":1816,"path":16,"size":1817,"width":1818,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713.png","small_jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713","small_jeremy_dahl_headshot - Jeremy Dahl.png",412.88,469,{"ext":19,"url":1820,"hash":1821,"mime":20,"name":1822,"path":16,"size":1823,"width":1824,"height":880},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/medium_jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713.png","medium_jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713","medium_jeremy_dahl_headshot - Jeremy Dahl.png",875.77,704,{"ext":19,"url":1826,"hash":1827,"mime":20,"name":1828,"path":16,"size":1829,"width":1830,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713.png","thumbnail_jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713","thumbnail_jeremy_dahl_headshot - Jeremy Dahl.png",49.86,146,"jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713",298.91,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/jeremy_dahl_headshot_Jeremy_Dahl_9e8ddd6713.png","2025-04-18T13:41:43.439Z",[],"-100","-101",{"id":167,"session":1839},{"id":207,"title":1840,"teaser":1841,"body":50,"createdAt":1842,"updatedAt":1842,"publishedAt":16,"url_path_id":1843,"contacts":1844,"url_path":1873},"Contrast-enhanced ultrasound for women's health","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">What is the first thing that comes to your mind when you think of ultrasound imaging?  Most of our research participants mentioned ultrasound during pregnancy. As they remember, ultrasound has been a familiar imaging modality for women’s health for a long time. However, the use of contrast-enhanced ultrasound (CEUS), an emerging ultrasound technique, is yet very limited. In this talk, four CEUS applications for women’s health will be introduced: two for breast and others for uterine cervix and placenta. Characterizing breast tumors has been a long-term research problem and CEUS may add diagnostic value. Not all breast cancer patients achieve favorable response from neoadjuvant chemotherapy (NAC) and early assessment of NAC response may improve patients’ survival by allowing earlier therapy modification minimizing unnecessary toxicity. CEUS has been shown potential to predict NAC response early. Cervical insufficiency (CI) describes the inability of the uterine cervix to retain a pregnancy in the absence of the signs and symptoms of clinical contractions, or labor, or both in the second trimester. Unfortunately, there is no objective test to evaluate cervical tissue strength to confirm a diagnosis of CI. Moreover, the diagnosis of CI cannot be made outside of pregnancy by any test. CEUS may help to assess cervix weakness by quantifying its perfusion and pressure in a non-pregnant state. Finally, CEUS may be used to monitor the development of placenta development by assessing placental hemodynamics. During gestation, the uterine vasculature undergoes numerous physiological modifications to produce the necessary increase in blood flow required to support the placental development. The preliminary evaluation results of CEUS bioeffects on the placenta will also be presented.  \u003C/span>\u003C/p>","2025-04-18T13:32:23.242Z","116",[1845],{"id":1846,"name":1847,"committee":16,"position":16,"affiliation":1848,"email":16,"biography":1849,"createdAt":1850,"updatedAt":1851,"url_path_id":1852,"contactPhoto":1853,"socialLinks":1871,"url_path":1872},65,"Kibo Nam","Thomas Jefferson University","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Kibo Nam received her B.E. degree in electrical and electronic engineering from Korea University, Seoul, South Korea, and her M.S. and Ph. D degrees in electrical and computer engineering from University of Wisconsin-Madison. Dr. Nam had her postdoctoral training at the University of Illinois at Urbana-Champaign and Thomas Jefferson University.  She also worked as a senior software engineer and product planning manager at Samsung Medison. She is currently working as a research associate professor at Thomas Jefferson University. Her research is focused on contrast-enhanced ultrasound, mainly subharmonic-aided pressure estimation (SHAPE). Her current SHAPE studies are for breast cancer therapy monitoring, assessment of carotid plaque risk, evaluation of placenta development, and detection of uterine cervix weakness.\u003C/span>\u003C/p>","2025-04-18T13:31:16.872Z","2025-08-29T23:34:54.448Z","115",{"id":977,"name":1854,"alternativeText":16,"caption":16,"width":1855,"height":1855,"formats":1856,"hash":1867,"ext":953,"mime":915,"size":1868,"url":1869,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1870,"updatedAt":1870},"large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421.jpg",714,{"small":1857,"thumbnail":1862},{"ext":953,"url":1858,"hash":1859,"mime":915,"name":1860,"path":16,"size":1861,"width":873,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421_90eb33cbe8.jpg","small_large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421_90eb33cbe8","small_large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421.jpg",40.65,{"ext":953,"url":1863,"hash":1864,"mime":915,"name":1865,"path":16,"size":1866,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421_90eb33cbe8.jpg","thumbnail_large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421_90eb33cbe8","thumbnail_large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421.jpg",6.71,"large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421_90eb33cbe8",74.28,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_Nam_Kibo_HEADSHOT_Kibo_Nam_0d0a24a421_90eb33cbe8.jpg","2025-08-29T23:34:52.121Z",[],"-95","-96",{"id":1875,"session":1876},56,{"id":533,"title":1877,"teaser":1878,"body":50,"createdAt":1879,"updatedAt":1880,"publishedAt":1881,"url_path_id":1882,"contacts":1883,"url_path":1924},"Double Vision: Advancing Quantitative On-Axis Modulus Estimation with DoPIo Ultrasound","\u003Cp>On-axis elasticity imaging methods are valued for their ability to assess tissue properties directly at the site of mechanical excitation, offering important advantages such as minimal spatial averaging for detailed tissue heterogeneity delineation and low displacement requirements for extended penetration or low output power demands. However, despite these strengths, conventional on-axis methods have been limited by their inability to provide quantitative modulus estimation, restricting their use to semi-quantitative analyses.  To address this limitation, Double Profile Intersection (DoPIo) ultrasound has been developed. DoPIo enables quantitative on-axis modulus estimation by utilizing two simultaneous, confocal beams of different widths to track ARF-induced displacements at the excitation site. The resulting paired displacement profiles capture scatterer shearing rates, which are mapped to elastic moduli through empirically derived and machine learned models. This presentation will highlight the development of and recent advancements to DoPIo, including the method’s extension to assessing mechanical anisotropy. In addition, the technology’s relevance to differentiating healthy, inflamed, and fibrotic kidney tissue, as well as characterizing skeletal muscle, will be demonstrated through ex vivo and in vivo studies in pigs and humans. Finally, ongoing challenges and future directions for further advancing DoPIo technology will be discussed, highlighting its potential to expand the capabilities and applications of ultrasound elasticity imaging.\u003C/p>","2025-08-18T19:45:42.147Z","2025-08-18T19:45:44.323Z","2025-08-18T19:45:44.316Z","193",[1884],{"id":320,"name":1885,"committee":16,"position":16,"affiliation":1886,"email":16,"biography":1887,"createdAt":1888,"updatedAt":1889,"url_path_id":1890,"contactPhoto":1891,"socialLinks":1922,"url_path":1923},"Caterina Gallippi","The University of North Carolina at Chapel Hill and North Carolina State University Lampe Joint Department of Biomedical Engineering","\u003Cp>Caterina M. Gallippi, Ph.D. is a William R. Kenan Jr. Distinguished Professor in the Lampe Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and North Carolina State University. She serves as the Director of the Unified Medical Ultrasound Technology Development (UNMUTED) NIH T32 predoctoral training program and leads the Ultrasound Research Association of North Carolina (ULTRASONC). Dr. Gallippi’s also leads a research laboratory that focuses on developing novel technologies for ultrasonic viscoelasticity imaging, advanced signal processing, and multidimensional motion tracking, with clinical applications focused on the diagnosis and management of atherosclerosis, musculoskeletal disorders, renal disease, and breast cancer. She earned a B.S.E. in electrical engineering from Princeton University and a Ph.D. in biomedical engineering from Duke University.  \u003C/p>","2024-10-23T04:09:48.763Z","2025-08-18T19:45:00.424Z","20",{"id":300,"name":1892,"alternativeText":16,"caption":16,"width":1893,"height":1894,"formats":1895,"hash":1918,"ext":1897,"mime":915,"size":1919,"url":1920,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1921,"updatedAt":1921},"Gallippi_2020Photo_small - Caterina Gallippi.jpeg",2632,3290,{"large":1896,"small":1903,"medium":1908,"thumbnail":1913},{"ext":1897,"url":1898,"hash":1899,"mime":915,"name":1900,"path":16,"size":1901,"width":1902,"height":958},".jpeg","https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd.jpeg","large_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd","large_Gallippi_2020Photo_small - Caterina Gallippi.jpeg",129.55,800,{"ext":1897,"url":1904,"hash":1905,"mime":915,"name":1906,"path":16,"size":1907,"width":1133,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd.jpeg","small_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd","small_Gallippi_2020Photo_small - Caterina Gallippi.jpeg",37.89,{"ext":1897,"url":1909,"hash":1910,"mime":915,"name":1911,"path":16,"size":1912,"width":1132,"height":880},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/medium_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd.jpeg","medium_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd","medium_Gallippi_2020Photo_small - Caterina Gallippi.jpeg",77.9,{"ext":1897,"url":1914,"hash":1915,"mime":915,"name":1916,"path":16,"size":1917,"width":1808,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd.jpeg","thumbnail_Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd","thumbnail_Gallippi_2020Photo_small - Caterina Gallippi.jpeg",5.54,"Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd",1041.4,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Gallippi_2020_Photo_small_Caterina_Gallippi_43850da9cd.jpeg","2025-02-13T17:03:01.296Z",[],"-10","-158",{"id":1926,"session":1927},58,{"id":620,"title":1928,"teaser":1929,"body":50,"createdAt":1930,"updatedAt":1931,"publishedAt":1932,"url_path_id":1933,"contacts":1934,"url_path":1956},"How Can AI-Driven Handheld Ultrasound Revolutionize Healthcare for Everyone ","\u003Cp style=\"text-align:justify;\">At PRAESENS, we are developing a portable ultrasound solution enhanced with AI, designed to serve the 4.7 billion people worldwide who currently lack access to diagnostic imaging. Born from field-driven insights and real-world constraints, our vision is rooted in practical experience across underserved settings. PRAESENS was originally established as a private foundation by Dr. Rudi Pauwels to strengthen frontline healthcare delivery through innovation. Building on this legacy, we are now working in close industrial partnership with one of the world’s leading medical imaging companies, who recognized the power of our approach in low-resource environments. Our mission is to democratize access to ultrasound by combining affordability, usability, and diagnostic performance—bringing lifesaving imaging capabilities to where they are needed most. \u003C/p>","2025-09-08T20:20:39.553Z","2025-09-08T20:20:42.344Z","2025-09-08T20:20:42.336Z","206",[1935],{"id":1936,"name":1937,"committee":16,"position":16,"affiliation":1938,"email":16,"biography":50,"createdAt":1939,"updatedAt":1939,"url_path_id":1940,"contactPhoto":1941,"socialLinks":1954,"url_path":1955},84,"Emmanuel Vidal","PRAESENS","2025-09-08T20:20:15.341Z","205",{"id":1942,"name":1943,"alternativeText":16,"caption":16,"width":331,"height":331,"formats":1944,"hash":1950,"ext":953,"mime":915,"size":1951,"url":1952,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1953,"updatedAt":1953},247,"1687848597511.jpg",{"thumbnail":1945},{"ext":953,"url":1946,"hash":1947,"mime":915,"name":1948,"path":16,"size":1949,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_1687848597511_ddfda16794.jpg","thumbnail_1687848597511_ddfda16794","thumbnail_1687848597511.jpg",4.84,"1687848597511_ddfda16794",7.22,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/1687848597511_ddfda16794.jpg","2025-09-08T20:20:12.955Z",[],"-162","-163",{"id":84,"groupTitle":1958,"sessions":1959},"Group 2",[1960,1991,2026],{"id":161,"session":1961},{"id":201,"title":1962,"teaser":1963,"body":50,"createdAt":1964,"updatedAt":1964,"publishedAt":16,"url_path_id":1965,"contacts":1966,"url_path":1990},"New ultrasound transducer concepts: pushing the boundaries in sensitivity, form factor and applications","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">The fast developments in AI, SAW/BAW filters, electronics and chips – both electronic and photonic – open up new frontiers for metrology. Chip structures are becoming more complex, 3D and include new materials. Heterogeneous integration is increasingly used to create aggregate chips. The more complex fabrication requires metrology with increased penetration depths at resolutions beyond those possible with traditional scanning acoustic microscopy (SAM). The solution requires innovative new metrology and transducer concepts.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">AI-based algorithms revolutionize the automated interpretation of ultrasound data – essential for echography to move outside of the domain of expert sonographers (i.e. the hospital). The latter development could help serve an aging population, limit rising health care costs and create new market opportunities. But the sonographer is also key for the correct aiming of the transducer. The automatic recording of the right data requires a large field-of-view and thus often a very large transducer aperture. To maintain good acoustic contact the transducer should be flexible. Outside the hospital space, the transducer should be cheap and come in a practical form factor – e.g. a patch. The solution requires new transducer and fabrication concepts. \u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Historically, in echography the key improvement driver was the hypothesis that higher image quality leads to better diagnoses and increased patient health. Here, a major parameter is the signal-to-noise-ratio (SNR). Diffraction and attenuation reduce pressure levels during propagation. Thus, an SNR increase yields detection at larger depths benefitting traditionally difficult to image patients (e.g. large/obese patients). Peak pressures are limited by safety standards. Thus, more sensitive transducers are required to increase SNR. However, despite continuous research in piezomaterials and electronics improvements in the Noise Equivalent Pressure (NEP) of electromechanical transducers has been limited. A way out could be a new transducer concept based on the interaction of light and sound. \u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Here we present an overview of three new transducer concepts researched at TNO. The first concept is Half-Wavelength Contact Acoustic Microscopy (HaWaCAM\u003Csup>TM\u003C/sup>) aimed at chip inspection. It uses solid-solid contact to side step the SNR and frequency limitations hampering traditional SAM concepts. The second concept is the PillarWave\u003Csup>TM\u003C/sup> flexible large-area ultrasound transducer fabrication process. It uses micro-structured PVDF-TrFE pillars and side steps some of the challenges of traditional transducer fabrication. The third concept is the Integrated Photonic Ultrasound Transducer (IPUT\u003Csup>TM\u003C/sup>). Literature reports similar devices with a NEP equal to the state-of-the-art but at >100x smaller footprints. Here, we cascade IPUTs to improve the NEP and side step limitations of conventional electromechanical transducers.\u003C/span>\u003C/p>\u003Cp>\u003Cbr>\u003Cbr> \u003C/p>","2025-04-18T13:48:26.188Z","123",[1967],{"id":1260,"name":1968,"committee":16,"position":16,"affiliation":1969,"email":16,"biography":1970,"createdAt":1971,"updatedAt":1972,"url_path_id":1973,"contactPhoto":1974,"socialLinks":1988,"url_path":1989},"Paul van Neer","TNO","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\"> Paul van Neer (1982) received his M.Sc. in Biomedical Engineering from Eindhoven University of Technology (Eindhoven, The Netherlands) in 2005. In 2010 he obtained his Ph.D. from the Erasmus University Rotterdam (Rotterdam, the Netherlands) for his work on the design of medical ultrasound hardware at the Erasmus Medical Center (Rotterdam, the Netherlands). In 2011 he joined TNO, an applied research institute in the Netherlands. Here, he worked at the Department of Process Intensification and Instrumentation on the development of ultrasonic measurement equipment, mainly for the chemical and oil and gas markets. In Jan. 2016 he joined the Department of Acoustics and Sonar (the Hague, the Netherlands). The emphasis of his work shifted towards the industrial/semicon, medical and sonar markets. Currently, Paul holds the position of Principal Scientist. His research interests focus on GHz acoustic metrology, sonars, flexible large-area ultrasound transducers, and metrology based on opto-acoustic sensors. Other research interests include (guided) wave propagation, nonlinear acoustics, ultrasonic signal and image processing, NDT, and transducer (array) design. His work resulted in multiple products/product lines and spin-outs. He (co-)authored 70+ patents and patent applications, and 40+ peer reviewed journal publications. Furthermore, the fruits of his work were presented in 125+ conference presentations.\u003C/span>\u003C/p>","2025-04-18T13:46:44.659Z","2025-08-29T23:30:15.364Z","122",{"id":1975,"name":1976,"alternativeText":16,"caption":16,"width":1977,"height":1977,"formats":1978,"hash":1984,"ext":953,"mime":915,"size":1985,"url":1986,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":1987,"updatedAt":1987},243,"Paul_van_Neer_Paul_van_Neer_b04a5edea4.jpg",498,{"thumbnail":1979},{"ext":953,"url":1980,"hash":1981,"mime":915,"name":1982,"path":16,"size":1983,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Paul_van_Neer_Paul_van_Neer_b04a5edea4_15798599be.jpg","thumbnail_Paul_van_Neer_Paul_van_Neer_b04a5edea4_15798599be","thumbnail_Paul_van_Neer_Paul_van_Neer_b04a5edea4.jpg",4.27,"Paul_van_Neer_Paul_van_Neer_b04a5edea4_15798599be",30.36,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Paul_van_Neer_Paul_van_Neer_b04a5edea4_15798599be.jpg","2025-08-29T23:30:11.908Z",[],"-102","-103",{"id":553,"session":1992},{"id":382,"title":1993,"teaser":1994,"body":1995,"createdAt":1996,"updatedAt":1997,"publishedAt":1998,"url_path_id":1999,"contacts":2000,"url_path":2025},"Extreme-Environment Sensor Systems for Industrial Applications","\u003Cp>Background, Motivation and Objective\u003Cbr>There is a pressing need for sensors and associated monitoring systems that can operate in industrial high-temperature (HT) harsh environments (HE) well above the 150 °C limit of traditional silicon (Si) microelectronics. Sensor applications in industries such as power generation, aerospace, oil and gas exploration, and high-temperature nuclear microreactors call for robust sensor units and systems that can provide long-term operation with little or no maintenance under high temperatures, vibration, oxidizing environments, temperature cycling, abrupt temperature shocks, and high irradiation conditions. Microwave acoustic materials and devices have been shown to withstand such conditions with minimal to no degradation in performance, while also offering the capability of wireless operation. In addition, wide bandgap semiconductors, such as silicon carbide (SiC) and gallium nitride (GaN), provide possibilities for sensor circuits that can function at high temperatures.\u003C/p>\u003Cp>Statement of Contribution/Methods\u003Cbr>This invited talk and paper discuss recent advances regarding microwave acoustic sensor systems capable of delivering temperature and strain monitoring in HT HE conditions, as well as neutron flux monitoring under intense irradiation and at high temperatures. In addition, HT HE SiC and GaN-based oscillators, along with thermoelectric generators (TEGs) for powering these systems, and integration with acoustic wave sensors are presented.\u003C/p>","\u003Cp>Results/Discussion\u003Cbr>The paper and presentation will discuss selected examples of the technological advances mentioned. For example, a test setup for seven HT HE surface acoustic wave resonator (SAWR) sensors exposed to neutron flux levels up to 2.0×10¹² n/(cm²·s) and temperatures up to 800 °C, and a representative in-situ sensor frequency response at 800 °C versus different reactor power levels will be shown and discussed. The versatility in measuring temperature, dynamic strain amplitude, and dynamic strain spectral components from a single SAWR will also be addressed through experimental implementation of such miniature and powerful device technology. In addition, results for GaN high electron mobility transistor (HEMT)-based oscillator circuit integrated with a bulk acoustic wave quartz resonator tested up to 400 °C will be presented. Also discussed is wireless interrogation in HT HE, and the use of TEGs under full insertion (hot and cold side) in the HE for biasing wide bandgap transistors under HT conditions.\u003C/p>","2025-06-11T17:11:25.976Z","2025-07-17T20:58:42.189Z","2025-07-17T13:39:13.810Z","160",[2001],{"id":2002,"name":2003,"committee":16,"position":16,"affiliation":2004,"email":16,"biography":2005,"createdAt":2006,"updatedAt":2007,"url_path_id":2008,"contactPhoto":2009,"socialLinks":2023,"url_path":2024},69,"Mauricio Pereira da Cunha","University of Maine, Dept. of Electrical and Computer Engineering and Frontier Institute for Research in Sensor Technology","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Mauricio Pereira da Cunha (M’89-SM’02-F’25) received the bachelor’s and master’s degrees (Hons.) in electrical engineering from the Escola Politécnica, Universidade de São Paulo, São Paulo, Brazil, in 1985 and 1989, respectively, and the Ph.D. degree (Dean’s Honor List) in electrical engineering from McGill University, Montreal, QC, Canada, in 1994. \u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">He is the Roger Clapp Castle and Virginia Averill Castle Professor of electrical and computer engineering with the University of Maine, Orono, ME, USA, and the  former CEO of Environetix Technologies Corporation, Orono, ME, USA. He was on sabbatical leave (1999/2000) at the University of Central Florida, Consortium for Applied Acoustoelectronic Technology (CAAT), Orlando, FL, USA, where he worked in cooperation with Piezotechnology Inc. (now MtronPTI), Orlando, FL, USA. Also worked with SAWTEK Inc. (now Qorvo), Orlando; McGill University, Montreal, PQ, Canada; as professor and researcher at Escola Politécnica, Dept. de Eng. Elétrica, Laboratório de Microeletrônica, Universidade de São Paulo; and with the Microwave Devices Research and Development Group, Nippon Electric Corporation (NEC), Guarulhos, SP, Brazil. His research interests include harsh environment sensors, wireless, gas, and biomedical sensors, antennas, microwave acoustic modeling, devices, and propagation (>250 publications). \u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Dr. Pereira da Cunha is a member of the IEEE, Sigma Xi, and the Brazilian Microwave Society. \u003C/span>\u003C/p>\u003Cp>\u003Cbr> \u003C/p>","2025-04-18T13:50:52.951Z","2025-08-29T23:26:26.633Z","124",{"id":2010,"name":2011,"alternativeText":16,"caption":16,"width":2012,"height":2012,"formats":2013,"hash":2019,"ext":953,"mime":915,"size":2020,"url":2021,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2022,"updatedAt":2022},242,"Mauricio_Headshot_Mauricio_Pereira_Da_Cunha_01103dffcb.jpg",367,{"thumbnail":2014},{"ext":953,"url":2015,"hash":2016,"mime":915,"name":2017,"path":16,"size":2018,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Mauricio_Headshot_Mauricio_Pereira_Da_Cunha_01103dffcb_e7a1ffdf27.jpg","thumbnail_Mauricio_Headshot_Mauricio_Pereira_Da_Cunha_01103dffcb_e7a1ffdf27","thumbnail_Mauricio_Headshot_Mauricio_Pereira_Da_Cunha_01103dffcb.jpg",4.17,"Mauricio_Headshot_Mauricio_Pereira_Da_Cunha_01103dffcb_e7a1ffdf27",16.12,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Mauricio_Headshot_Mauricio_Pereira_Da_Cunha_01103dffcb_e7a1ffdf27.jpg","2025-08-29T23:26:24.460Z",[],"-104","-134",{"id":363,"session":2027},{"id":241,"title":2028,"teaser":2029,"body":50,"createdAt":2030,"updatedAt":2030,"publishedAt":16,"url_path_id":2031,"contacts":2032,"url_path":2057},"Scanning X-acoustic Microscopy: Detection of Multi-Physical Properties at nm-µm","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Ultrasonic testing is commonly employed to assess the mechanical properties and structural characteristics of target materials, as the interaction between ultrasonic waves and matter is fundamentally governed by mechanical principles. Furthermore, the spatial resolution of such techniques is inherently constrained by the wavelength of the ultrasonic waves due to Rayleigh diffraction limit. When attempting to measure additional physical properties of the material and achieve a significant enhancement in resolution, conventional ultrasonic methods face substantial limitations.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">The key to achieving this is to find other types waves or particles that can detect such physical properties and modulate them in time domain as input, such as pulsed electron beams, pulsed force, or pulsed light, etc., which can interact with the material to generate acoustic signals carrying targeted information. By integrating techniques such as focused scanning, lock-in amplification, and microscopic imaging, methodologies like scanning electron-acoustic microscopy (SEAM), scanning probe-acoustic microscopy (SPAM), and scanning near-field optoacoustic microscopy (SNOAM) can be developed. These approaches enable us to surpass the Rayleigh diffraction limit, thereby enabling the characterization of various physical properties at the micro- or nanoscale.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cbr>\u003Cspan style=\"background-color:transparent;color:#000000;\">This talk will introduce the progress of our laboratory's work in this field. Based on SEAM, the interaction between electrons and matter enables high-definition imaging of the subsurface electric and magnetic domains as well as the subsurface microstructure of bone tissue. Based on SPAM, the nanoscale force interaction between probes and material surfaces/subsurfaces enables mapping the hydrophilicity of the material, and the residual stress, as well as the microstructure of nucleoskeleton. Based on SNOAM, in addition to investigating molecular light absorption characteristics, it is possible to explore the non-radiative recombination processes of electron-hole pairs in semiconductor materials at nanoscale.\u003C/span>\u003Cbr> \u003C/p>","2025-04-18T13:56:15.694Z","126",[2033],{"id":2034,"name":2035,"committee":16,"position":16,"affiliation":2036,"email":16,"biography":2037,"createdAt":2038,"updatedAt":2038,"url_path_id":2039,"contactPhoto":2040,"socialLinks":2055,"url_path":2056},70,"Qian Cheng","Tongji University","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Prof. Dr. CHENG Qian received the B.S. degree in applied physics, M.S. and Ph.D. degree in acoustics from Tongji University, China, in 2000, 2003 and 2006, respectively. Now she is a Distinguished Professor at the Institute of Acoustics, School of Physical Science and Engineering of Tongji University in China. And she is the member of the Board of the Acoustical Society of China (ASC), and serves as vice director of ASC Testing Acoustics Branch, vice director of Acoustic Education Branch, and standing member of Biomedical Ultrasound Engineering Branch in ASC. In addition, she is the vice president of Shanghai Acoustical Society, member of Instrument Development Branch of Chinese Ultrasonic Medical Engineering Society. She was awarded the Wei Mo'an Acoustics Prize in 2019.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Her research focuses on acoustic/optical detection, including biomedical photoacoustic detection, super-resolution near-field acoustic imaging, acoustic field manipulation and visualization, etc. Recently, her lab has developed multimodal photoacoustic imaging systems, including photoacoustic imaging mode and photoacoustic spectroscopy mode, which can specifically detect a variety of macromolecules in biological tissues. Compared to traditional clinical imaging techniques, her technique has achieved non-invasive in vivo diagnosis of the differentiation of benign and malignant tumors and the grading of malignant tumors, as well as surgical navigation and long-term therapeutic effect evaluation. Besides, the Cheng’s lab has invented or discovered 1) scanning near-field photoacoustic microscopy, scanning probe acoustic microscopy, scanning differential electron acoustic microscopy, etc., to achieve the detection of internal physical properties and structures of cells, semiconductors and other materials and functional devices with nanometer resolution to micron resolution; 2) 3D acoustic field optical CT imaging system, to realize non-invasive and dynamic imaging of arbitrary 3D acoustic field in liquid, which is especially meaningful for acoustic metamaterials research; 3) fiber optic ultrasonic sensing system, to realize high-precision measurement of wideband ultrasonics, which can be used for online nondestructive monitoring and diagnosis of structures and devices; 4) and ultrasonic cell stimulation system, to realize neuron excitation, stem cell proliferation and directional differentiation, cartilage damage repair, etc. To date, she has co-authored three professional books, published more than 100 peer-reviewed papers, given more than 60 talks at academic conferences and patented more than 30 Chinese and international inventions.\u003C/span>\u003C/p>\u003Cp>\u003Cbr> \u003C/p>","2025-04-18T13:54:48.626Z","125",{"id":2041,"name":2042,"alternativeText":16,"caption":16,"width":2043,"height":2044,"formats":2045,"hash":2051,"ext":19,"mime":20,"size":2052,"url":2053,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2054,"updatedAt":2054},128,"Screenshot 2025-04-18 085508.png",185,254,{"thumbnail":2046},{"ext":19,"url":2047,"hash":2048,"mime":20,"name":2049,"path":16,"size":2050,"width":1234,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Screenshot_2025_04_18_085508_8f7bdaccf5.png","thumbnail_Screenshot_2025_04_18_085508_8f7bdaccf5","thumbnail_Screenshot 2025-04-18 085508.png",29.87,"Screenshot_2025_04_18_085508_8f7bdaccf5",20.17,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Screenshot_2025_04_18_085508_8f7bdaccf5.png","2025-04-18T13:54:20.972Z",[],"-105","-106",{"id":91,"groupTitle":2059,"sessions":2060},"Group 3",[2061],{"id":793,"session":2062},{"id":401,"title":2063,"teaser":2064,"body":2065,"createdAt":2066,"updatedAt":2066,"publishedAt":16,"url_path_id":2067,"contacts":2068,"url_path":2097},"IDTs-based active holograms: from selective 2D and 3D manipulation to complex  pattern formation","\u003Cp style=\"text-align:justify;\">Acoustic tweezers are a promising technique for the contactless manipulation of objects both in vitro and in vivo, as they are biocompatible, label-free, and capable of remotely handling objects ranging in size from millimeters down to micrometers [1]. Recently, holographic techniques [2] have emerged as powerful tools for shaping acoustic fields, enabling the generation of complex wavefronts to perform advanced tasks such as three-dimensional particle\u003Cbr>manipulation [3,4] and two- or three-dimensional patterning [2,5]. These approaches generally rely on either passive devices that modulate the phase of an input signal generated by a piezoelectric source [2], or on active transducer arrays driven by dedicated electronics that independently control each element's phase and/or amplitude [3,4]. However, in both cases, the achievable resolution is often limited by the inherent constraints in frequency, which restricts their capability to manipulate individual microscopic entities—such as cells or microorganisms—or to achieve micrometer-scale patterning precision.\u003Cbr>\u003Cbr> \u003C/p>","\u003Cp style=\"text-align:justify;\">In this presentation, we will explore how Interdigital Transducers (IDTs)—metallic electrodes sputtered onto the surface of a piezoelectric substrate and traditionally used to generate planar Surface Acoustic Waves—can be reconfigured as binary holograms to synthesize complex 3D wavefields with unprecedented resolution [6,7]. We will then demonstrate how these wavefields can be exploited for high-precision tasks, including 2D and 3D selective\u003Cbr>manipulation, orientation control, and micropatterning of microparticles and cells. These capabilities open new perspectives for applications in tissue engineering, targeted drug delivery, and acoustic spectroscopy.\u003C/p>","2025-06-12T17:17:53.419Z","164",[2069],{"id":2070,"name":2071,"committee":16,"position":16,"affiliation":2072,"email":16,"biography":2073,"createdAt":2074,"updatedAt":2074,"url_path_id":2075,"contactPhoto":2076,"socialLinks":2095,"url_path":2096},79,"Michael Baudoin","Université de Lille (France)","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:#ffffff;color:#121512;\">After completing a Ph.D. at Sorbonne University in the field of acoustics and a postdoctoral position at Ecole Polytechnique in France in microfluidics, Michael Baudoin became an Assistant Professor and later a Professor at the University of Lille, where he established the FILMS team at the IEMN laboratory. His research focuses on the intersection of acoustics, interfacial fluid mechanics, and microtechnology, encompassing theoretical, numerical, experimental, and application aspects in these domains. Specifically, he has pioneered the development of selective acoustic tweezers using IDT holograms for the manipulation of microparticles and cells, as well as utilizing surface acoustic waves for the manipulation of fluids and particles on surfaces. More recently, his research has delved into exploring analogies between acoustics and quantum mechanics, as well as drawing parallels between the mechanics of drops on soap films and cosmology. In 2019, he was appointed a Junior Fellow of the Institut Universitaire de France. Beyond academia, Michael Baudoin has been actively engaged in technology transfer, founding the VISION startup to commercialize Cleardrop ultrasonic technology for the integrated cleaning of optical devices and solar panels.\u003C/span>\u003C/p>\u003Cp>\u003Cbr> \u003C/p>","2025-06-12T17:14:02.951Z","163",{"id":2077,"name":2078,"alternativeText":16,"caption":16,"width":2079,"height":2079,"formats":2080,"hash":2091,"ext":953,"mime":915,"size":2092,"url":2093,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2094,"updatedAt":2094},179,"BAUDOIN Michael - michael baudoin.jpg",512,{"small":2081,"thumbnail":2086},{"ext":953,"url":2082,"hash":2083,"mime":915,"name":2084,"path":16,"size":2085,"width":873,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_BAUDOIN_Michael_michael_baudoin_e9e92ab953.jpg","small_BAUDOIN_Michael_michael_baudoin_e9e92ab953","small_BAUDOIN Michael - michael baudoin.jpg",23.32,{"ext":953,"url":2087,"hash":2088,"mime":915,"name":2089,"path":16,"size":2090,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_BAUDOIN_Michael_michael_baudoin_e9e92ab953.jpg","thumbnail_BAUDOIN_Michael_michael_baudoin_e9e92ab953","thumbnail_BAUDOIN Michael - michael baudoin.jpg",3.46,"BAUDOIN_Michael_michael_baudoin_e9e92ab953",23.96,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/BAUDOIN_Michael_michael_baudoin_e9e92ab953.jpg","2025-06-12T17:13:24.006Z",[],"-135","-136",{"id":320,"groupTitle":2099,"sessions":2100},"Group 4",[2101,2137,2168],{"id":769,"session":2102},{"id":187,"title":2103,"teaser":2104,"body":50,"createdAt":2105,"updatedAt":2105,"publishedAt":16,"url_path_id":2106,"contacts":2107,"url_path":2136},"XBAR Filter Technologies for Wi-Fi Application","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">This talk presents recent advances of laterally excited shear mode bulk acoustic wave resonators (XBARs). Since Dr. Plessky and colleagues published the first XBAR in 2019, a lot of attention has been paid to XBARs because of their unique features, such as high frequency and large electromechanical coupling factor, which are considered to be difficult to achieve with conventional SAWs and BAWs. Although the XBAR characteristics have been reported by means of simulations and demonstration using simplified resonators and filters, there have been some issues pointed out, such as the intrinsically its fragile-looking suspended structure, manufacturability, reliability for mechanical and power durability, which have not been reported on the feasibility of XBARs as a practical use level in mass production. Characteristics, manufacturability, and reliability of XBAR technologies applied to filters for Wi-Fi applications are presented.\u003C/span>\u003C/p>","2025-04-18T13:59:46.447Z","128",[2108],{"id":2109,"name":2110,"committee":16,"position":16,"affiliation":2111,"email":16,"biography":2112,"createdAt":2113,"updatedAt":2114,"url_path_id":2115,"contactPhoto":2116,"socialLinks":2134,"url_path":2135},71,"Tetsuya Kimura","Resonant Inc. A Murata Company","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Tetsuya Kimura was born in Shimane, Japan in 1972. He received the B.S. and M.S. degrees in mechanical engineering from Okayama University, Okayama, Japan, in 1995 and 1997, respectively, and the Ph.D. degree in electrical engineering from Chiba University, Chiba, Japan, in 2019. In 1997, he joined Murata Manufacturing Co., Ltd., Kyoto, Japan, where he had been researching and developing acoustic wave devices. He joined Resonant Inc. (a Murata affiliate) in San Mateo, USA, in 2022, and has continued to be involved in the research and development of acoustic wave devices as a Fellow of the company.\u003C/span>\u003C/p>","2025-04-18T13:59:00.739Z","2025-08-29T23:22:21.097Z","127",{"id":2117,"name":2118,"alternativeText":16,"caption":16,"width":2119,"height":2119,"formats":2120,"hash":2131,"ext":953,"mime":915,"size":1829,"url":2132,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2133,"updatedAt":2133},241,"large_T_KIMURA_K_K_af3f8eb224.jpg",656,{"small":2121,"thumbnail":2126},{"ext":953,"url":2122,"hash":2123,"mime":915,"name":2124,"path":16,"size":2125,"width":873,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_large_T_KIMURA_K_K_af3f8eb224_d4c4e534e4.jpg","small_large_T_KIMURA_K_K_af3f8eb224_d4c4e534e4","small_large_T_KIMURA_K_K_af3f8eb224.jpg",31.72,{"ext":953,"url":2127,"hash":2128,"mime":915,"name":2129,"path":16,"size":2130,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_large_T_KIMURA_K_K_af3f8eb224_d4c4e534e4.jpg","thumbnail_large_T_KIMURA_K_K_af3f8eb224_d4c4e534e4","thumbnail_large_T_KIMURA_K_K_af3f8eb224.jpg",4.97,"large_T_KIMURA_K_K_af3f8eb224_d4c4e534e4","https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_T_KIMURA_K_K_af3f8eb224_d4c4e534e4.jpg","2025-08-29T23:22:18.987Z",[],"-107","-108",{"id":99,"session":2138},{"id":281,"title":2139,"teaser":2140,"body":50,"createdAt":2141,"updatedAt":2141,"publishedAt":16,"url_path_id":2142,"contacts":2143,"url_path":2167},"Gas Cluster Beam: High-Precision Trimming for RF Filter Devices in High-Volume Manufacturing","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">The global expansion of 5G and demand for higher mobile speed has created significant new RF filtering challenges. These include higher frequencies, higher bandwidth, more complex filtering requirements such as multiplexers and antennaplexers, lower insertion loss, etc. Many of these challenges demands extremely high precision of film thickness and frequency control in high-volume manufacturing. At higher frequency, the film thickness becomes thinner, thus leading to higher sensitivity for frequency variation.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Gas Cluster Beam (GCB) technology has been used in trimming of RF filters. There are some unique features with GCB, including, physically driven chemical reaction, high etch rate, low energy per molecule, low power without the need of wafer cooling. This leads to a lower mass of the wafer scanner, which makes its maneuver easier. With a high acceleration voltage of up to 60kV, the potential wafer charge of dozens of volts will have no impact of the etch rate. However, if the acceleration voltage is up to 1000V, the fluctuation of wafer charge voltage will lead to fluctuation of etch rate. Low thermal energy also means that GCB process will not lead to photoresist hardening, thus rendering no issue in photoresist removal. \u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">In some trimming applications, zero trimming amount is locally required. We have developed a unique way to control beam power down to zero. This also gives us a control knob to dynamically adjust beam power so that we can handle higher gradient which cannot by handled with mechanical way. Zero Trim capability also allows faster wafer turnaround without the need of larger scanning area, thus improving throughput.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">To have a beam to handle large gradients in the input maps, the GCB beam is focused down to 3.5mm in FWHM (Full Width Half Max). The smaller the beam, the larger the resolution is. The critical parameters to the trimming performance are beam size, beam shape, and alignment. We have developed novel ways to align beam and characterize the beam profile. Beam tuning can be done with this new metrics and gives better trimming performance.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Many hardware and software improvements have been implemented in the UltraTrimmer tool platform to overcome the challenges in HVM. GCB technology has been widely used in SAW, BAW, FBAR and Thin-Film SAW production. It is currently expanding the application field to MEMS, EUV mask blanks and AR lens production.\u003C/span>\u003C/p>","2025-06-12T17:29:56.869Z","166",[2144],{"id":2145,"name":2146,"committee":16,"position":16,"affiliation":2147,"email":16,"biography":2148,"createdAt":2149,"updatedAt":2149,"url_path_id":2150,"contactPhoto":2151,"socialLinks":2165,"url_path":2166},80,"Henry Yue","TEL","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Henry is a Member of Technical Staff in the Technology Strategy Management group of TMEA (TEL Manufacturing and Engineering America), a TEL subsidiary. He has over 25 years of experiences in semiconductor manufacturing and equipment technology, having worked in the fields of plasma etching, photolithography, low-k materials, Gas Cluster Beam (GCB), Advanced Process Control (APC), etc. He has been an innovative problem solver with 28 US patents issued. Henry received his bachelor and master degrees from Tsinghua University, and Ph.D. in Chemical Engineering from the University of Texas at Austin. Henry loves math and was a math coach for his son’s middle and high schools during his spare time. Dozens of his students went on to enroll at MIT and Harvard.\u003C/span>\u003C/p>","2025-06-12T17:28:50.280Z","165",{"id":2152,"name":2153,"alternativeText":16,"caption":16,"width":253,"height":2154,"formats":2155,"hash":2161,"ext":19,"mime":20,"size":2162,"url":2163,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2164,"updatedAt":2164},180,"Screenshot 2025-06-12 122840.png",197,{"thumbnail":2156},{"ext":19,"url":2157,"hash":2158,"mime":20,"name":2159,"path":16,"size":2160,"width":1163,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Screenshot_2025_06_12_122840_ce879938a4.png","thumbnail_Screenshot_2025_06_12_122840_ce879938a4","thumbnail_Screenshot 2025-06-12 122840.png",39.69,"Screenshot_2025_06_12_122840_ce879938a4",18.35,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Screenshot_2025_06_12_122840_ce879938a4.png","2025-06-12T17:28:26.919Z",[],"-137","-138",{"id":2169,"session":2170},54,{"id":306,"title":2171,"teaser":2172,"body":50,"createdAt":2173,"updatedAt":2174,"publishedAt":2175,"url_path_id":2176,"contacts":2177,"url_path":2201},"Advances and Challenges in Growth of LiNbO3-LiTaO3 Thin Films for Acoustic Devices","\u003Cp>The state-of-the-art control/tuning/measurement of Li nonstoichiometry in deposited LiNbO3 (LN) films were addressed for the first time and the stoichiometry homogeneity of <0.05 mol% /reproducibility of high-quality LN films at 4’' wafer scale (never demonstrated before) was attained by direct liquid injection (DLI) CVD. CVD growth also assured highly homogeneous thickness on the wafer scale. The epitaxial growth of LN films with unique orientations in the substrate plane (necessary for guided wave applications) in the case of X, Y, and Z orientations (according to IEEE convention) was optimized. In addition, we have succeeded in epitaxially growing new Y128° and Y52° orientations of LN with a single orientation in the plane of the substrate, this is the most used crystal orientation for RF SAW filters. In the literature, only the epitaxy/texture of the Z orientation, (not having good piezoelectric properties) on bottom electrodes has been successful. We have obtained the epitaxial/textured growth of Y33°-LN (the orientation offering optimized electromechanical coupling for thickness mode of bulk acoustic waves) on Pt electrodes. LN film orientation is defined only by the LaNiO3 seed layer and any substrate/structure and electrode, able to withstand LN deposition conditions, can be used. However, the Si substrate was replaced by sapphire or LN substrate in these HBAR and SMR devices in order to reduce thermal stresses and to eliminate chemical interactions of LN with Pt adhesion layers (Ta, Ti, TiO2) and SiO2/Si. Further effort was done to stabilize the heterostructures based on grown LN layers, electrodes and Si substrates by introducing new adhesion layers for Pt electrode and by stress engineering. In order to bring deposited epitaxial (singel crystalline) LN films towards the acoustic devices requiring single crystalline LN films on standard platforms, the layer transfer process is under development. This includes epitaxial growth of LN films on LN substrates with sacrificial layer then bonding on freely chosen structure and liberation of LN film from the growth template by chemical etching.\u003C/p>","2025-07-03T04:27:12.382Z","2025-07-03T04:27:14.598Z","2025-07-03T04:27:14.584Z","173",[2178],{"id":2179,"name":2180,"committee":16,"position":16,"affiliation":2181,"email":16,"biography":2182,"createdAt":2183,"updatedAt":2183,"url_path_id":2184,"contactPhoto":2185,"socialLinks":2199,"url_path":2200},72,"Ausrine Bartasyte","Institute FEMTO-ST/C2N/IUF","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:#ffffff;color:#333333;\">Dr. A. Bartasyte is a Full Professor at FEMTO-ST Institute / UMLP, Junior Chair for Innovation at IUF, and associated researcher at C2N. She received her PhD at LMGP, Grenoble INP, conducted postdoctoral research at Oxford University, and completed a sabbatical at Harvard and Penn State Universities. She has over 20 years of expertise in the deposition of epitaxial multifunctional oxides using liquid injection MOCVD and rf puttering. Her current research focuses on Li(K)Nb(Ta)O₃ thin films and single crystals for acoustic, energy harvesting, and photonic applications.\u003C/span>\u003C/p>","2025-04-18T14:02:00.725Z","129",{"id":2186,"name":2187,"alternativeText":16,"caption":16,"width":431,"height":393,"formats":2188,"hash":2195,"ext":19,"mime":20,"size":2196,"url":2197,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2198,"updatedAt":2198},130,"Screenshot 2025-04-18 090316.png",{"thumbnail":2189},{"ext":19,"url":2190,"hash":2191,"mime":20,"name":2192,"path":16,"size":2193,"width":2194,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Screenshot_2025_04_18_090316_eecc03c50a.png","thumbnail_Screenshot_2025_04_18_090316_eecc03c50a","thumbnail_Screenshot 2025-04-18 090316.png",34.45,144,"Screenshot_2025_04_18_090316_eecc03c50a",10.35,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Screenshot_2025_04_18_090316_eecc03c50a.png","2025-04-18T14:01:40.795Z",[],"-109","-142",{"id":28,"groupTitle":2203,"sessions":2204},"Group 5",[2205,2247,2295],{"id":356,"session":2206},{"id":596,"title":2207,"teaser":2208,"body":50,"createdAt":2209,"updatedAt":2209,"publishedAt":16,"url_path_id":2210,"contacts":2211,"url_path":2246},"Histotripsy Instrumentation for Non-invasive Cancer Treatment","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Histotripsy is a non-invasive, non-ionizing, and mechanical ultrasound ablation technique that was invented by Dr. Xu and her colleagues at the University of Michigan. Using microsecond-length, high-pressure ultrasound pulses applied from outside the body and focused to the target diseased tissue, histotripsy produces a cluster of energetic cavitation microbubbles in the target tissue using the endogenous nanometer gas pockets. The rapid expansion and collapse of the cavitation microbubbles produce high local mechanical strain and stress to disrupt the target tissue into liquid-appearing acellular debris with millimeter accuracy. Pre-clinical studies have shown that ultrasound image-guided histotripsy can noninvasively and mechanically disrupt the target tumor while preserving the large normal vessels and other critical structures (e.g., bile ducts). Histotripsy tumor ablation results in tumor reduction or complete eradication, increased survival benefit, and reduced metastasis (abscopal effect). Histotripsy also induces significant innate and adaptive immune response and abscopal effect in murine tumor models. Dr. Xu’s work has led to the FDA approval of non-invasive histotripsy treatment of liver tumors using the Edison\u003Csup>TM\u003C/sup> system ultrasound image-guided robotic assisted histotripsy platform (HistoSonics) in October 2023. There are ongoing multi-center clinical trials in the U.S. and Europe on histotripsy treatment of renal tumors and pancreatic tumors using the Edison\u003Csup>TM\u003C/sup> platform. As histotripsy uses ultrasound parameters entirely different from HIFU thermal ablation, Dr. Xu’s group has developed specialized ultrasound transducers and electronic drivers for histotripsy. She will talk about the instrumentation develop of histotripsy, the latest pre-clinical and clinical progress on histotripsy cancer treatment, and her journal to bring this technology from bench to bedside.  \u003C/span>\u003C/p>","2025-04-18T14:09:27.911Z","135",[2212],{"id":2213,"name":2214,"committee":16,"position":16,"affiliation":2215,"email":16,"biography":2216,"createdAt":2217,"updatedAt":2218,"url_path_id":2219,"contactPhoto":2220,"socialLinks":2244,"url_path":2245},75,"Zhen Xu","University of Michigan","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Dr. Zhen Xu is the Li Ka Shing Endowed Professor of Biomedical Engineering, and Professor of Radiology and Neurosurgery at the University of Michigan, Ann Arbor, MI. Her research focuses on ultrasound therapy and imaging. She is a pioneer and world leader of histotripsy. She has developed histotripsy for cancer, neurological, and cardiovascular applications. Her work has led to the FDA approval of histotripsy treatment of liver tumors. She has been elected as Fellow of National Academy of Inventors (NAI), Fellow of American Institute of Medicine and Bioengineering (AIMBE), and IEEE. She received the IEEE Ultrasonics, Ferroelectrics, and Frequency Control (UFFC) Outstanding Paper Award in 2006, Frederic Lizzi Award from The International Society of Therapeutic Ultrasound (ISTU) in 2015, Lockhart Memorial Prize for Cancer Research in 2020, and IEEE Carl Hellmuth Hertz Ultrasonics Award in 2024. She has published 130+ peer-reviewed journal papers and has been awarded $40+ millions of external grant funding. She has 36 issued US and international patents. She is a principal investigator of grants funded by NIH, Office of Navy Research, American Cancer Association, and Focused Ultrasound Foundation.\u003C/span>\u003C/p>","2025-04-18T14:08:49.806Z","2025-08-29T23:14:57.014Z","134",{"id":2221,"name":2222,"alternativeText":16,"caption":16,"width":2223,"height":2223,"formats":2224,"hash":2240,"ext":1897,"mime":915,"size":2241,"url":2242,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2243,"updatedAt":2243},240,"Zhen Xu_headshot.jpeg",760,{"small":2225,"medium":2230,"thumbnail":2235},{"ext":1897,"url":2226,"hash":2227,"mime":915,"name":2228,"path":16,"size":2229,"width":873,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_Zhen_Xu_headshot_b5df4a53d8.jpeg","small_Zhen_Xu_headshot_b5df4a53d8","small_Zhen Xu_headshot.jpeg",26.34,{"ext":1897,"url":2231,"hash":2232,"mime":915,"name":2233,"path":16,"size":2234,"width":880,"height":880},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/medium_Zhen_Xu_headshot_b5df4a53d8.jpeg","medium_Zhen_Xu_headshot_b5df4a53d8","medium_Zhen Xu_headshot.jpeg",46.93,{"ext":1897,"url":2236,"hash":2237,"mime":915,"name":2238,"path":16,"size":2239,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Zhen_Xu_headshot_b5df4a53d8.jpeg","thumbnail_Zhen_Xu_headshot_b5df4a53d8","thumbnail_Zhen Xu_headshot.jpeg",4.83,"Zhen_Xu_headshot_b5df4a53d8",43.41,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Zhen_Xu_headshot_b5df4a53d8.jpeg","2025-08-29T23:14:54.001Z",[],"-114","-115",{"id":2248,"session":2249},50,{"id":181,"title":2250,"teaser":2251,"body":50,"createdAt":2252,"updatedAt":2252,"publishedAt":16,"url_path_id":2253,"contacts":2254,"url_path":2294},"The silicon-photonics acoustic detector (SPADE): Advancing wideband ultrasound technology","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">The performance of piezoelectric ultrasound transducers is inherently constrained by tradeoffs between sensitivity, size, and bandwidth, limiting their versatility in advanced imaging applications. The Silicon-Photonics Acoustic Detector (SPADE) offers a novel approach that alleviates these limitations by enabling miniaturized, ultra-wideband ultrasound reception. When combined with optoacoustic ultrasound generation, SPADE unlocks new imaging capabilities, facilitating novel configurations for high-resolution optoacoustic tomography and ultrasound. This presentation will delve into the fundamental principles of SPADE technology and showcase its potential imaging applications.\u003C/span>\u003C/p>","2025-04-18T14:04:04.256Z","131",[2255],{"id":2256,"name":2257,"committee":16,"position":16,"affiliation":2258,"email":16,"biography":2259,"createdAt":2260,"updatedAt":2260,"url_path_id":2261,"contactPhoto":2262,"socialLinks":2292,"url_path":2293},73,"Amir Rosenthal","Technion - Israel Institute of Technology","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Amir Rosenthal is an Associate Professor at the Department of Electrical and Computer Engineering at the Technion – Israel Institute of Technology. He performed his Ph.D. at the Technion in the field of fiber optics and 2 postdocs at Harvard Medical School and Technical University of Munich in the field of biophotonics, as a Marie Curie Fellow. He is currently the head of the Laboratory for Biomedical Imaging and Sensing, which focuses on the development of novel optical and ultrasound technologies for biomedical applications. His main scientific contributions are in the field optoacoustic tomography and optical technologies for ultrasound detection.\u003C/span>\u003C/p>","2025-04-18T14:03:30.617Z","130",{"id":1412,"name":2263,"alternativeText":16,"caption":16,"width":2264,"height":2265,"formats":2266,"hash":2288,"ext":1897,"mime":915,"size":2289,"url":2290,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2291,"updatedAt":2291},"profile pic - Amir Rosenthal.jpeg",2048,1365,{"large":2267,"small":2273,"medium":2278,"thumbnail":2283},{"ext":1897,"url":2268,"hash":2269,"mime":915,"name":2270,"path":16,"size":2271,"width":958,"height":2272},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_profile_pic_Amir_Rosenthal_f7106b04b6.jpeg","large_profile_pic_Amir_Rosenthal_f7106b04b6","large_profile pic - Amir Rosenthal.jpeg",92.96,667,{"ext":1897,"url":2274,"hash":2275,"mime":915,"name":2276,"path":16,"size":2277,"width":873,"height":1140},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_profile_pic_Amir_Rosenthal_f7106b04b6.jpeg","small_profile_pic_Amir_Rosenthal_f7106b04b6","small_profile pic - Amir Rosenthal.jpeg",33.1,{"ext":1897,"url":2279,"hash":2280,"mime":915,"name":2281,"path":16,"size":2282,"width":880,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/medium_profile_pic_Amir_Rosenthal_f7106b04b6.jpeg","medium_profile_pic_Amir_Rosenthal_f7106b04b6","medium_profile pic - Amir Rosenthal.jpeg",60.31,{"ext":1897,"url":2284,"hash":2285,"mime":915,"name":2286,"path":16,"size":2287,"width":1146,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_profile_pic_Amir_Rosenthal_f7106b04b6.jpeg","thumbnail_profile_pic_Amir_Rosenthal_f7106b04b6","thumbnail_profile pic - Amir Rosenthal.jpeg",10.49,"profile_pic_Amir_Rosenthal_f7106b04b6",269.8,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/profile_pic_Amir_Rosenthal_f7106b04b6.jpeg","2025-04-18T14:03:12.282Z",[],"-110","-111",{"id":1740,"session":2296},{"id":261,"title":2297,"teaser":2298,"body":50,"createdAt":2299,"updatedAt":2299,"publishedAt":16,"url_path_id":2300,"contacts":2301,"url_path":2317},"Novel High-frequency Transducer and System for High-resolution Ultrasound Imaging","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">High imaging resolution can be achieved through high-frequency ultrasound, which operates at center frequencies of 7-15 MHz. This range has been extensively adopted in clinical applications and plays a critical role in diagnosing thyroid, breast, and musculoskeletal diseases. Furthermore, ultra-high frequency ultrasound, ranging from 15-50 MHz or even higher, is increasingly being integrated into clinical practice. It offers high-resolution imaging with resolutions of less than 100 microns, making it particularly valuable for examining the skin, eyes, blood vessels, and other structures, thereby demonstrating significant potential for broader applications. This talk will focus on the research advancements in high-frequency ultrasound imaging transducers, imaging methodologies, and imaging systems.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Several innovative high-frequency transducers and systems have been developed to address new imaging challenges and scenarios. We proposed a transparent ultrasonic transducer design using our developed transparent Pb(In\u003Csub>1/2\u003C/sub>Nb\u003Csub>1/2\u003C/sub>)O\u003Csub>3\u003C/sub>-Pb(Mg\u003Csub>1/3\u003C/sub>Nb\u003Csub>2/3\u003C/sub>)O\u003Csub>3\u003C/sub>-PbTiO\u003Csub>3\u003C/sub> (PIN-PMN-PT) crystals. Our fabrication technique incorporates quartz-glass-andepoxy matching layers with low-resistance indium-tin-oxide electrodes through a brass-ring based structure, enabling a high frequency (28.5 MHz), wide bandwidth (78%), and enhanced pulse-echo sensitivity (2.5 V under 2-μJ pulse excitation). \u003C/span>\u003Cspan style=\"background-color:transparent;color:#231f20;\">In addition, we developed a high-performance focused IVUS transducer using Pb(In\u003Csub>1/2\u003C/sub>Nb\u003Csub>1/2\u003C/sub>)O\u003Csub>3\u003C/sub>-Pb(Sc\u003Csub>1/2\u003C/sub>Nb\u003Csub>1/2\u003C/sub>)O\u003Csub>3\u003C/sub>-PbTiO\u003Csub>3\u003C/sub> (PIN-PSN-PT) textured ceramics with both high electromechanical performance and high Curie temperature.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Our transparent ultrasonic transducer demonstrates a four-fold enhancement in photoacoustic detection sensitivity when compared to the LiNbO\u003Csub>3\u003C/sub>-based counterpart, leading to a 13 dB improvement of signal-to-noise ratio in microvascular photoacoustic imaging. This enables dynamic monitoring of mouse cerebral cortex microvasculature during seizures at 0.8 Hz frame rates over a 1.5 × 1.5 mm\u003Csup>2\u003C/sup> field-of-view. \u003C/span>\u003Cspan style=\"background-color:transparent;color:#231f20;\">The developed focused IVUS transducer operates at 42 MHz with an -6 dB bandwidth of 72%, featuring a 0.6x0.6 mm\u003Csup>2\u003C/sup> aperture while maintaining an electrical impedance of approximately 40–60ohm. The axial and lateral resolutions characterized by wire phantom imaging are 45 and 208 um, respectively. The acoustic pressure generated by the focused IVUS transducer is 1.4 times higher than that of its planar counterpart. \u003C/span>\u003Cspan style=\"background-color:transparent;color:#000000;\">It is anticipated that these cutting-edge high-frequency ultrasound imaging technologies will soon become standard features in ultrasound equipment, contributing significantly to the advancement of precision medical diagnostics.\u003C/span>\u003C/p>","2025-04-18T14:07:12.870Z","133",[2302],{"id":2303,"name":2304,"committee":16,"position":16,"affiliation":2305,"email":16,"biography":2306,"createdAt":2307,"updatedAt":2307,"url_path_id":2308,"contactPhoto":2309,"socialLinks":2315,"url_path":2316},74,"Weibao Qiu","Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Science","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Weibao Qiu obtained his Ph.D. degree from The Hong Kong Polytechnic University, in 2012. He joined the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences the same year and was promoted to Full Professor in early 2018. His research interests are novel ultrasound transducer and system for biomedical imaging and therapy. Several high frequency ultrasonic transducers have been developed including transparent high frequency transducer, textured ceramics based transducer, intravascular/intracardiac transducer, high frequency linear array and 2D matrix array. Several novel high frequency ultrasound device and system have also been developed including capsule ultrasound device, intravascular ultrasound system, small animal high frequency array imaging systems. He has established an integrated R&D framework \"Transducers-Imaging Methods-Systems\" for high-resolution ultrasound. Prof Qiu has published 83 SCI papers (including 1 in Nature communications and 34 in IEEE Transactions) and has been granted 35 invention patents. Several high-resolution imaging technologies have been transformed into innovative products (obtaining 4 registration certificates). He is the founder of Shenzhen Hyus Meditec Co., Ltd., a company specializing in advanced ultrasound solutions (novel ultrasound transducers, and imaging systems).\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cbr>\u003Cspan style=\"background-color:transparent;color:#000000;\">Prof. Qiu has been continually active in the UFFC society for more than 15 years. He serves on the Technical Program Committee (Group 5) of IEEE International Ultrasonics Symposium (IUS), and is an Associate Editor of the IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. He is the leading guest editor of TUFFC Special Issue on “Recent advances in ultrasound technology for brain imaging and therapy”. In 2020, he received a grant “Outstanding Youth Fund of National Natural Science Foundation of China”, for high resolution ultrasound imaging, which has great influence in China. He is the Outstanding Member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences.He establishes a new ultrasound research laboratory: “Shenzhen key laboratory of ultrasound imaging and therapy”, and now is part of “State Key Laboratory of Biomedical Imaging Science and System”. He is vice chair of the Medical Ultrasound Engineering Division at the Chinese Society of Biomedical Engineering. In addition, he maintains strong ties with academia and industry across China’s ultrasound community. He is the Chief Administrator of the Chinese Ultrasound Association (in Wechat app, the group has 484 active Chinese ultrasound researchers).\u003C/span>\u003C/p>\u003Cp>\u003Cbr> \u003C/p>","2025-04-18T14:06:00.877Z","132",{"id":1200,"name":2310,"alternativeText":16,"caption":16,"width":1212,"height":1513,"formats":16,"hash":2311,"ext":19,"mime":20,"size":2312,"url":2313,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2314,"updatedAt":2314},"Screenshot 2025-04-18 090639.png","Screenshot_2025_04_18_090639_0c7843af1d",7.75,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Screenshot_2025_04_18_090639_0c7843af1d.png","2025-04-18T14:05:27.642Z",[],"-112","-113",{"id":358,"groupTitle":2319,"sessions":2320},"Clinical",[2321,2370,2406],{"id":2322,"session":2323},52,{"id":439,"title":2324,"teaser":2325,"body":50,"createdAt":2326,"updatedAt":2326,"publishedAt":16,"url_path_id":2327,"contacts":2328,"url_path":2369},"Ultrafast Ultrasound imaging of Brain Tumors: Clinical opportunities in- and outside of the neurosurgical operating room","\u003Cp style=\"text-align:justify;\">Neurosurgeons faced with a brain tumor in the operating room have one clear goal: removing as much of the tumor as possible, without damaging functional brain regions. Ultrafast ultrasound imaging - a new high-resolution, mobile neuroimaging technique - has the potential to revolutionize the way we treat brain tumors by visualizing tumor and healthy brain microvasculature as well as functional brain areas in real-time.\u003Cbr>\u003Cbr>This talk will provide an overview of our team’s combined efforts in the last years to translate ultrafast ultrasound from bench to bedside. We will first discuss results from intra-operative in-human measurements during awake brain surgeries for a range of tumor types. I will highlight how our intra-operative results remain convincing when validated against gold standard techniques such as fMRI and Electro-cortical Stimulation Mapping (ESM). The clinician and patient’s challenge does not end with the surgical procedure alone. Ultrafast Ultrasound has the potential to also change the post-surgical follow-up period, when patients question whether the tumor is growing back or whether chemoradiation treatment is successful. Using clinically approved plastic cranioplasties post-surgery, we demonstrate our ability to monitor tumor regrowth and brain functionality outside of the operating consistently over a period of nearly 2 years. This work demonstrates the potential of ultrafast ultrasound to change the way we treat brain tumors, both in- and outside the operating room, ultimately improving patients’ outcomes.\u003C/p>","2025-04-18T13:16:35.969Z","110",[2329],{"id":947,"name":2330,"committee":16,"position":16,"affiliation":2331,"email":16,"biography":2332,"createdAt":2333,"updatedAt":2333,"url_path_id":2334,"contactPhoto":2335,"socialLinks":2367,"url_path":2368},"Sadaf Soloukey","Erasmus MC Rotterdam","\u003Cp style=\"text-align:justify;\">Sadaf Soloukey (MD/PhD) is a neurosurgical resident at the Erasmus Medical Center in Rotterdam, The Netherlands and a co-founding member of Center for Ultrasound Brain Imaging @ Erasmus MC (CUBE). Sadaf’s research focuses on translating functional Ultrasound imaging (fUSi), from bench to bedside, or in her case, into the neurosurgical operating room and beyond. During her PhD, Sadaf has demonstrated multiple successful examples of in-human applications of fUSi, such as during awake brain surgeries to guide tumor resections. Her most recent work, published in Science Advances (2025), shows how fUSi is also a mobile technique, which can be used to monitor human brain activity outside of the operating room, in a walking subject. Sadaf has a strong passion for multidisciplinary collaboration to improve clinical care through technological innovation. Her ultimate dream is to be able to use the techniques she helped developed herself, as a way to improve the neurosurgical care - and ultimately – the quality of life of her patients.\u003C/p>","2025-04-18T13:12:36.285Z","109",{"id":1513,"name":2336,"alternativeText":16,"caption":16,"width":2337,"height":2338,"formats":2339,"hash":2363,"ext":953,"mime":915,"size":2364,"url":2365,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2366,"updatedAt":2366},"Headshot_Soloukey - Sadaf Soloukey.jpg",1920,1080,{"large":2340,"small":2346,"medium":2352,"thumbnail":2358},{"ext":953,"url":2341,"hash":2342,"mime":915,"name":2343,"path":16,"size":2344,"width":958,"height":2345},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20.jpg","large_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20","large_Headshot_Soloukey - Sadaf Soloukey.jpg",45.1,563,{"ext":953,"url":2347,"hash":2348,"mime":915,"name":2349,"path":16,"size":2350,"width":873,"height":2351},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20.jpg","small_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20","small_Headshot_Soloukey - Sadaf Soloukey.jpg",16.08,281,{"ext":953,"url":2353,"hash":2354,"mime":915,"name":2355,"path":16,"size":2356,"width":880,"height":2357},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/medium_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20.jpg","medium_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20","medium_Headshot_Soloukey - Sadaf Soloukey.jpg",29.2,422,{"ext":953,"url":2359,"hash":2360,"mime":915,"name":2361,"path":16,"size":2362,"width":1022,"height":233},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20.jpg","thumbnail_Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20","thumbnail_Headshot_Soloukey - Sadaf Soloukey.jpg",5.86,"Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20",115.43,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Headshot_Soloukey_Sadaf_Soloukey_0edbc4aa20.jpg","2025-04-18T13:11:27.046Z",[],"-89","-90",{"id":1023,"session":2371},{"id":541,"title":2372,"teaser":2373,"body":50,"createdAt":2374,"updatedAt":2374,"publishedAt":16,"url_path_id":2375,"contacts":2376,"url_path":2405},"Ultrasound Vascular Flow Imaging: Pushing Boundaries, Shaping the Future","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Diagnostics in vascular surgery still rely heavily on anatomical imaging techniques such as contrast-enhanced computed tomography (CT) and magnetic resonance (MR) imaging. However, these methods provide limited information on hemodynamics, which play a crucial role in the onset and progression of atherosclerotic disease. Currently, flow imaging is restricted to duplex ultrasound, which offers only one-dimensional flow estimates at the center of the vessel and is highly operator-dependent. This highlights the need for advanced flow imaging techniques that can provide more comprehensive and reliable hemodynamic assessments.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">While computational fluid dynamics (CFD) and phase-contrast MR imaging (PC-MRI) have demonstrated potential in flow visualization, their clinical adoption remains limited due to high computational demands, long acquisition times, and cost considerations. Ultrasound, in contrast, is widely used in clinical practice due to its accessibility, cost-effectiveness, and real-time imaging capabilities. However, conventional ultrasound techniques are not well suited for detailed flow pattern visualization.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Recent advancements in plane wave ultrasound imaging offer a promising solution. By significantly increasing the frame rate, these techniques enable flow imaging through particle imaging velocimetry (PIV) algorithms, allowing for the assessment of complex flow patterns in real-time. Initial clinical studies have demonstrated the feasibility of this approach, showing good agreement with PC-MRI, both without contrast agents in superficial arteries and with contrast enhancement in deeper vessels.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Despite these promising developments, several challenges remain before widespread clinical implementation can be achieved. Future research should focus on identifying clinically relevant flow parameters that correlate with disease progression and outcomes. Additionally, efforts should be made to integrate these techniques into commercially available ultrasound systems, ensuring ease of use and accessibility in routine clinical practice. Overcoming these barriers could pave the way for a new era of hemodynamic assessment in vascular surgery, ultimately improving patient diagnosis and treatment planning.\u003C/span>\u003C/p>\u003Cp>\u003Cbr> \u003C/p>","2025-04-18T13:23:02.352Z","112",[2377],{"id":994,"name":2378,"committee":16,"position":16,"affiliation":2379,"email":16,"biography":2380,"createdAt":2381,"updatedAt":2382,"url_path_id":2383,"contactPhoto":2384,"socialLinks":2403,"url_path":2404},"Michel Reijnen","Department of Surgery, Rijnstate Arnhem and Multi-Modality Medical Imaging Group, University of Twente, Enschede, The Netherlands","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"background-color:transparent;color:#000000;\">Prof. dr. Michel Reijnen (MD, PHD)  finished his (endo)vascular training in January 2004 and joined the Rijnstate Hospital in Arnhem, the Netherlands in 2007. He has involved in multiple trials in the endovascular area and initiator and principal investigator of various national and international multicentre randomized trials and prospective cohort studies. Being an early adaptor, he has been involved in the early phases of various innovations in the endovascular field, including the Covered Endovascular Reconstruction of the Aortic bifurcation technique. There is a close collaboration with Twente University, Enschede, The Netherlands, where he is Professor of ‘Endovascular Imaging and Innovation at the Multi-Modality Medical Imaging Group. The main focus here is flow quantification in relation to clinical pathologies using various techniques including Particle Imaging Velocimetry. He has published over 250 peer reviewed manuscripts and book chapters and is member of the editorial board of several journals and a regular faculty member of several international symposia, including the Veith Symposium, the Leipzig International Course and the Charing Cross Symposium. He has been supervisor of nineteen completed PhD projects with twelve ongoing projects.  In addition, he is consultant of both large companies as well as several small scale start-up companies.\u003C/span>\u003C/p>","2025-04-18T13:21:57.052Z","2025-08-29T23:12:01.657Z","111",{"id":2385,"name":2386,"alternativeText":16,"caption":16,"width":2387,"height":2387,"formats":2388,"hash":2399,"ext":953,"mime":915,"size":2400,"url":2401,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2402,"updatedAt":2402},239,"large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f.jpg",675,{"small":2389,"thumbnail":2394},{"ext":953,"url":2390,"hash":2391,"mime":915,"name":2392,"path":16,"size":2393,"width":873,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f_47474622f7.jpg","small_large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f_47474622f7","small_large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f.jpg",30.15,{"ext":953,"url":2395,"hash":2396,"mime":915,"name":2397,"path":16,"size":2398,"width":887,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f_47474622f7.jpg","thumbnail_large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f_47474622f7","thumbnail_large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f.jpg",4.04,"large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f_47474622f7",52.56,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/large_Michel_Reijnen_10_2_Michel_Reijnen_4aa716303f_47474622f7.jpg","2025-08-29T23:11:59.385Z",[],"-91","-92",{"id":2407,"session":2408},57,{"id":479,"title":2409,"teaser":50,"body":2410,"createdAt":2411,"updatedAt":2412,"publishedAt":2413,"url_path_id":2414,"contacts":2415,"url_path":2444},"What Has Driven Innovation in Cardiovascular Ultrasound – Inspiration, Serendipity, Collaboration,  Technology, Commerce, or Clinical Need?","\u003Cp style=\"text-align:justify;\">Technological progress in diagnostic imaging has been astounding, since the first experiments with cardiac ultrasound by the physicist Hellmuth Hertz and the physician Inge Edler in Lund in 1953. They met through connections when Edler wanted advice about possible imaging of the heart valves, because his patients were dying from early attempts at cardiac surgery. They were\u003Cbr>fortunate in the availability of ultrasonic devices for detecting flaws in metal, and in personal connections with the company that manufactured the equipment, but progress was slow. Hertz\u003Cbr>commented in 1973 that different physicians had very different opinions on the relative importance of possible additional features and no clear answer could be given to the designing\u003Cbr>engineers in industry. It was Christophorus Buijs Ballot from Utrecht – not Christian Doppler – who demonstrated the change in pitch of sound waves from a moving target, in experiments reported in 1845. He was trying to disprove the theory that Doppler had published two years earlier, itself an extension of work by James Bradley in 1727, concerning the red shift of light from distant stars. ‘Doppler’ echocardiography can be traced to Shigeo Satomura in Japan in the early 1950s, but he was aiming to analyse motion of the heart walls. Directional flowmeters were made in the 1960s, and it was not until the 1970s that range-gated Doppler was developed in Norway in order to obtain physiological data for the validation of a computer model of the circulation. Estimation of pressure gradients was proposed in 1976 by Jarle Holen, who had worked as an engineer on Boeing’s supersonic aircraft project before qualifying in medicine – but it was the cardiologist Liv Hatle in Trondheim who had the vision and application really to exploit the new tool for clinical haemodynamic assessment. Doppler myocardial imaging resulted from another joint initiative of physicists and clinicians, in Edinburgh. Progress has been enabled by advances in engineering, but projects that are led by technological breakthroughs risk becoming tools without clinical impact – especially in the era of sophisticated image-processing software with integrated artificial intelligence and machine learning algorithms. For effective innovation, funding must be available for open collaborations between engineers and clinicians, with subsequent engagement by industry. Planning for regulatory approval means demonstrating clinical value.\u003C/p>","2025-08-28T16:04:13.070Z","2025-09-03T13:12:31.739Z","2025-08-28T16:04:15.678Z","197",[2416],{"id":214,"name":2417,"committee":16,"position":16,"affiliation":16,"email":16,"biography":2418,"createdAt":2419,"updatedAt":2419,"url_path_id":2420,"contactPhoto":2421,"socialLinks":2442,"url_path":2443},"Alan Fraser","\u003Cp style=\"text-align:justify;\">Consultant Cardiologist, University Hospital of Wales, Cardiff, UK Emeritus Professor of Cardiology, Cardiff University Visiting Professor, Katholieke Universiteit Leuven, Belgium Chairman, Regulatory Affairs Committee, Biomedical Alliance in Europe Scientific Coordinator of EU Horizon 2020 project CORE-MD (Coordination of Research and Evidence for Medical Devices)\u003C/p>","2025-08-28T15:59:33.019Z","196",{"id":2422,"name":2423,"alternativeText":16,"caption":16,"width":2424,"height":2425,"formats":2426,"hash":2438,"ext":953,"mime":915,"size":2439,"url":2440,"previewUrl":16,"provider":23,"provider_metadata":16,"createdAt":2441,"updatedAt":2441},235,"Picture1.jpg",482,682,{"small":2427,"thumbnail":2433},{"ext":953,"url":2428,"hash":2429,"mime":915,"name":2430,"path":16,"size":2431,"width":2432,"height":873},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/small_Picture1_33ebc83e5e.jpg","small_Picture1_33ebc83e5e","small_Picture1.jpg",16.03,353,{"ext":953,"url":2434,"hash":2435,"mime":915,"name":2436,"path":16,"size":2437,"width":1084,"height":887},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/thumbnail_Picture1_33ebc83e5e.jpg","thumbnail_Picture1_33ebc83e5e","thumbnail_Picture1.jpg",2.79,"Picture1_33ebc83e5e",24.34,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/ius25/Picture1_33ebc83e5e.jpg","2025-08-28T15:59:11.346Z",[],"-159","-160",{"data":2446,"meta":2447},{"id":267,"heading":262,"createdAt":268,"updatedAt":269,"publishedAt":270,"url_path_id":271,"url_path":274,"contentType":89},{},1778853068836]